In May 2025, the European Chemicals Agency (ECHA) released the fourth edition of the Catalogue of borderline cases between articles and substances/mixtures.

China updated to the Inventory of Existing Chemical Substances in China through additions and changes in usage.

On May 13, 2025, the US Environmental Protection Agency (EPA) announced significant adjustments to the data submission deadlines under the Toxic Substances Control Act (TSCA) for per- and polyfluoroalkyl substances (PFAS) and PFAS-containing products.

China’s chemical inventory of existing chemical substances is IECSC, which stands for the Inventory of Existing Chemical Substances Produced or Imported in China (IECSC). There are two parts of IECSC, public part and classified/confidential part. Companies can check out the public part by themselves and shall only enquire Authorities for classified/confidential part. If substances are not listed in the public part, companies have to submit a formal enquiry to SCC to check whether a substance is listed in the confidential part. The enquiry costs 3000 RMB.

After the US Occupational Safety and Health Administration (OSHA) released the new Hazard Communication Standard (HCS) regulations on May 20, 2024, it has become crucial to understand what precautions and new changes there are in the US hazardous chemical labels. This article covers the elements that labels for a hazardous chemical in the United States must contain.

To boost compliance with Turkey's KKDIK chemical regulations, the Draft Implementation Rules was published in early 2025.

According to the convention, the production of these two substances is theoretically banned globally starting from January 1, 2026.

Recently, the Ministry of Labor in South Korea, under Article 108(3) of the Industrial Safety and Health Act and Clause 153 of the enforcement rules, officially issued Announcement No. 2025-162, disclosing 72 new chemical substances manufactured and imported in the first quarter of 2025. The hazards, risks, annual manufacturing and import volumes, and measures to prevent worker health damage related to these substances were detailed. Manufacturers and importers of new chemical substances are required to submit a report on the hazards and risks to the Ministry of Labor 30 days before manufacturing or importing these materials.

Japan announced adjustments to the Priority Assessment Chemical Substances List and the requirements for reporting production quantities.

On April 29, 2025 , the European Chemicals Agency (ECHA) unveiled a proposal to restrict the use of carcinogenic hexavalent chromium (Cr(VI)) substances across the EU. The measure aims to safeguard human health and the environment from the cancer risks associated with these chemicals.