ECHA Releases 2025-2027 Substance Evaluation Rolling Plan (CoRAP), 28 Substances Listed

On March 25, 2025, the European Chemicals Agency (ECHA) officially published an updated version of the Community Rolling Action Plan (CoRAP) for 2025-2027. The plan aims to systematically evaluate 28 chemical substances that may pose risks to human health or the environment under Articles 44–48 of the EU REACH Regulation ((EC) No 1907/2006). The evaluations will be led by competent authorities of 8 Member States and span 2025 to 2027.

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Highlights of the Plan

1. New and Extended Evaluations

13 new substances have been added to the evaluation list for the first time, focusing on their potential risks.
18 substances are carried over from the CoRAP 2024-2026 Update published in March 2024, with 12 substances postponed to post-2025 due to pending supplementary data submissions (dossier evaluation requests) from companies.

2. Evaluation Timeline

2025: 8 substances (including 2 grouped analogues) begin evaluation.
2026: 15 substances enter the evaluation process.
2027: 5 substances start evaluation.

Note: The lists for 2026 and 2027 may be adjusted in future CoRAP updates.

3. 3 Substances Withdrawn

The first substance was withdrawn as existing data sufficiently addressed initial concerns.
For the second substance, additional requirements were raised through dossier evaluation. If unresolved, it may be relisted in CoRAP.
The third substance (Reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives) has been formally classified as a Substance of Very High Concern (SVHC) and will undergo stricter regulatory controls.

Newly Added and Withdrawn Substances

Year	EC/List Number	CAS Number	Substance Public Name	Initial grounds for concern
2025	201-116-6	78-42-2	Tris(2-ethylhexyl) phosphate	suspected C, potential endocrine disruptor, wide dispersive use, consumer use, exposure of workers, and environmental exposure.
2025	201-114-5	78-40-0	Triethyl phosphate	suspected C, suspected M, suspected R, potential endocrine disruptor wide dispersive use, consumer use, exposure of workers, environmental exposure, and high (aggregated) tonnages.
2025	265-929-8	65799-47-5	[3-(2,3 epoxypropoxy)propyl]dime thoxymethylsilane	suspected M exposure of workers
2025	220-780-8	2897-60-1	[3-(2,3 epoxypropoxy)propyl]dieth oxymethylsilane	suspected M exposure of workers
2025	208-047-0	506-61-6	Potassium dicyanoargentate	suspected R, potential endocrine disruptor, other suspected human health hazard, wide dispersive use exposure of workers, and environmental exposure.
2026	238-098-4	14228-73-0	1,4-bis[(2,3 epoxypropoxy)methyl]cycl ohexane	suspected M, wide dispersive use, consumer use, and exposure of workers.
2026	203-183-7	104-19-8	N,N,4-trimethylpiperazine- 1-ethylamine	suspected R, other hazard based concerns, wide dispersive use, and exposure of workers.
2026	201-148-0	78-83-1	2-methylpropan-1-ol	suspected R, other hazard based concerns, wide dispersive use consumer use, exposure of workers, exposure of sensitive populations, environmental exposure, and high (aggregated) tonnage.
2026	407-000-3	127519-17-9	A mixture of branched and linear C7-C9 alkyl 3-[3 (2H-benzotriazol-2-yl)-5 (1,1-dimethylethyl)-4 hydroxyphenyl]propionates	suspected PMT/vPvM, wide dispersive use, and environmental exposure.
2026	400-830-7	-	A mixture of: a-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl ?-hydroxypoly(oxyethylene); a-3-(3-(2H-benzotriazol-2 yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-?-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene)	suspected PMT/vPvM, wide dispersive use, and environmental exposure.
2026	400-820-2	84268-33-7	Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate	suspected PMT/vPvM, wide dispersive use, and environmental exposure.
2026	916-914-6	-	Reaction mass of Octyl-3-[3-tert-butyl-4-hydroxy-5-(5-chloro-2H-benzotriazole-2-yl)phenyl]propionate and 2-Ethylhexyl-3-[3-tert-butyl-4-hydroxy-5-(5-chloro-2H-benzotriazole-2-yl)phenyl]propionate	suspected PMT/vPvM, wide dispersive use, and environmental exposure.
2026	confidential	-	Di-substituted tert-alkyl 3- [3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoate	suspected PMT/vPvM, wide dispersive use, and environmental exposure.
Withdr awn	202-860-4	100-52-7	Benzaldehyde	suspected M, wide dispersive use, consumer use, and exposure of workers.
Withdr awn	205-739-4	149-44-0	Sodium hydroxymethanesulphinate	suspected C, suspected M, suspected R, wide dispersive use, exposure of workers, and high (aggregated) tonnage.
Withdr awn	421-820-9	192268-65-8	Reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives	suspected PBT/vPvB

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