Japan announced adjustments to the Priority Assessment Chemical Substances List and the requirements for reporting production quantities.

On April 29, 2025 , the European Chemicals Agency (ECHA) unveiled a proposal to restrict the use of carcinogenic hexavalent chromium (Cr(VI)) substances across the EU. The measure aims to safeguard human health and the environment from the cancer risks associated with these chemicals.

The Draft Law on Hazardous Chemicals Safety of was formally included in the NPC Standing Committee’s 2025 Legislative Work Plan.

Measures revolve around three guiding principles: enhancing scientific research, fulfilling legal obligations with improved communication, and building collaborative partnerships.

The reporting system is expected to be operational by December 2025.

ECHA added six new substance testing proposals and opened a public consultation period, inviting stakeholders to submit comments by June 2.

The Vietnamese National Assembly unveiled the second draft of the revised Law on Chemicals.

On April 3, 2025, during a meeting of the Competent Authorities for REACH and CLP (CARACAL), the European Commission proposed the latest amendments to the REACH Regulation, sparking strong objections from the European Chemical Industry Council (Cefic), the European Federation of Construction Chemicals (EFCC), and the International Fragrance Association (IFRA). The three industry associations directly criticized the revision draft for contradicting the EU's policy objectives of enhancing industrial competitiveness, warning that it could severely impact small and medium-sized enterprises (SMEs).

In April 2025, ECHA released its 2024 annual work report, showcasing its significant achievements and challenges in chemical regulation over the past year.

In April 2025, New Mexico passed the Per- and Poly-Fluoroalkyl Substances (PFAS) Protection Act to strengthen regulation of PFAS chemicals, safeguarding human health and the environment. Below are the key provisions of the legislation.