On March 5, 2024, the Scientific Committee on Consumer Safety (SCCS) of the European Union issued the preliminary opinion (SCCS/1663/24) on the inhalation toxicity of the fragrance ingredient Acetylated Vetiver Oil – AVO (CAS No 84082-84-8, EC No 282-031-1) in sprayable cosmetic products. The deadline for comments is set on 3 May 2024.
The SCCS concludes the following:
In light of the data provided concerning inhalation toxicity, does the SCCS consider Acetylated Vetiver Oil (AVO) safe when used in sprayable cosmetic products with intended maximum concentrations (IMCs) of 0.9% (w/w) in fragrance pump sprays, 0.05% (w/w) in deodorant sprays and 0.1% (w/w) in hairsprays and body lotion sprays?
Having considered the data provided concerning inhalation toxicity and aggregate exposure, the SCCS considers Acetylated Vetiver Oil (AVO) (with 1% alpha11 tocopherol) safe when used at the intended maximum concentrations (IMCs) of 0.9%(w/w) in fragrance pump sprays, 0.05% (w/w) in deodorant sprays and 0.1% (w/w) in hairsprays and body lotion sprays. The findings of an in vitro study using Mucilair™ also support this conclusion.
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